To My Beloved Dad

Dad,,,it's been a hundred days you left us all,
it's been a hundred nights we spent without seeing you around us,
it's been a hundred sun & moon come up while we're praying for you the best.

Dad,,,may ALLAH put you in HIS side,
skip all the falls you've done,
give you happiness with all of your kindness.

But Dad,,,I still and will miss you so,
miss to see you,
miss to tell you that I love you,
miss to say sorry to you for all jerk I've done that made you sad & disappointed,

Please Dad, forgive me for all,
keep remind me in your life,
keep loving me like you used to,
keep hoping me to get together again in the future.

Daddy,,,I love you

Really Proud

Yesterday was my greatest day, having my son winning his school championship. One again, he made me proud of him, really proud,,,
Bring it on!!, when he got home bringing that trophy with him,,,
After those hard moment waiting a long list of number calling and seeing him so upset on his friends raise up to the stage to get the prize, while his number was not being called yet. Could not imagine how I would make him happy if he never won that championship,,,,could not imagine what come up if he went home with nothing,,,oh GOD,,,I sigh,,,,
Then on a last minute before end,,,,,mentioned a number who got the second winner, really unexpected,,,it was my son's number!!!!,,,,Hooray!!!! I shouted!!! Finally I can see my son on the stage with that trophy raised,,,,Suddenly my sad turn to be happy in a second,,,,
Thanks GOD,,,,for giving me my son's happiness,,,,

A Killer

Cancer is a sudden and hidden killer. It takes no long time to be spread out to the whole organs of the body. It is hidden inside the body so that no one can see it. And it is suddenly take away some one we love in a minute. Felt there is only so little time we got, even we don't have it just to fight it, then we must surrender.

HIGH DOSAGE VITAMIN E STIMULATE LUNG CANCER

Vitamin E is one of the most important vitamins for preventing an aging, but if it is consumed in high dosage it will increase the risk for lung cancer. The benefit of vitamin has already known as an antioxidant for protecting cells from free radical items. But, researchers from USA have indicated that consuming high dosage of vitamin will make pro oxidant that make oxidation and destroying cells. Research conducted in USA by involving 77 thousands participant indicated that consuming vitamin E 400 mg per day in long period can improve a risk for lung cancer up to 28% particularly for smoker.

What is thyroid cancer?

Thyroid cancer is a malignant neoplasm that develops from thyroid cells. In the normal state, new thyroid cells are constantly being produced in a regulated way to replace cells that die off. In the course of this process, certain cells may become abnormal, escaping from cycles of growth. When these abnormal cells continue to multiply and expand in an uncontrolled fashion, they become a tumor or neoplasm ("neo" = new, "plasm" = growth). If a neoplasm grows but remains contained within it without spreading outward to invade normal tissue, it is considered to be benign. If a neoplasm grows and spreads outward to invade normal tissue, it is considered to be malignant, in other words, a cancer.

Causes of Cancer

Cancer is a diverse class of diseases which differ widely in their causes and biology. The common thread in all known cancers is the acquisition of abnormalities in the genetic material of the cancer cell and its progeny. Research into the pathogenesis of cancer can be divided into three broad areas of focus. The first area of research focuses on the agents and events which cause or facilitate genetic changes in cells destined to become cancer. Second, it is important to uncover the precise nature of the genetic damage, and the genes which are affected by it. The third focus is on the consequences of those genetic changes on the biology of the cell, both in generating the defining properties of a cancer cell, and in facilitating additional genetic events, leading to further progression of the cancer.

Chemical carcinogens

Cancer pathogenesis is traceable back to DNA mutations that impact cell growth and metastasis. Substances that cause DNA mutations are known as mutagens, and mutagens that cause cancers are known as carcinogens. Particular substances have been linked to specific types of cancer. Tobacco smoking is associated with lung cancer and bladder cancer. Prolonged exposure to asbestos fibers is associated with mesothelioma.

Many mutagens are also carcinogens, but some carcinogens are not mutagens. Alcohol is an example of a chemical carcinogen that is not a mutagen. Such chemicals are thought to promote cancers through their stimulating effect on the rate of cell mitosis. Faster rates of mitosis leaves less time for repair enzymes to repair damaged DNA during DNA replication, increasing the likelihood of a genetic mistake. A mistake made during mitosis can lead to the daughter cells receiving the wrong number of chromosomes

Decades of research have demonstrated the strong association between tobacco use and cancers of many sites, making it perhaps the most important human carcinogen. Hundreds of epidemiological studies have confirmed this association. Further support comes from the fact that lung cancer death rates in the United States have mirrored smoking patterns, with increases in smoking followed by dramatic increases in lung cancer death rates and, more recently, decreases in smoking followed by decreases in lung cancer death rates in men.

Ionizing radiation

Sources of ionizing radiation, such as radon gas, can cause cancer. Prolonged exposure to ultraviolet radiation from the sun that lead to melanoma and other skin malignancies.

Radiation from mobile phones has been conjectured for some time as a cause but this theory has not gained mainstream support. Nevertheless some experts caution against prolonged exposure.

Infectious diseases

Some cancers can be caused by infection with pathogens. Many cancers originate from a viral infection; this is especially true in animals such as birds, but also in humans, as viruses are responsible for 15% of human cancers worldwide. The main viruses associated with human cancers are human papillomavirus, hepatitis B and hepatitis C virus, Epstein-Barr virus, and human T-lymphotropic virus. Experimental and epidemiological data imply a causative role for viruses and they appear to be the second most important risk factor for cancer development in humans, exceeded only by tobacco usage. The mode of virally-induced tumors can be divided into two, acutely-transforming or slowly-transforming. In acutely transforming viruses, the virus carries an overactive oncogene called viral-oncogene (v-onc), and the infected cell is transformed as soon as v-onc is expressed. In contrast, in slowly-transforming viruses, the virus genome is inserts near a proto-oncogene in the host genome. The viral promoter or other transcription regulation elements then cause overexpression of that proto-oncogene. This induces uncontrolled cell division. Because the site of insertion is not specific to proto-oncogenes and the chance of insertion near any proto-oncogene is low, slowly-transforming viruses will cause tumors much longer after infection than the acutely-transforming viruses.

Hepatitis viruses, including hepatitis B and hepatitis C, can induce a chronic viral infection that leads to liver cancer in 0.47% of hepatitis B patients per year (especially in Asia, less so in North America), and in 1.4% of hepatitis C carriers per year. Liver cirrhosis, whether from chronic viral hepatitis infection or alcoholism, is associated with the development of liver cancer, and the combination of cirrhosis and viral hepatitis presents the highest risk of liver cancer development. Worldwide, liver cancer is one of the most common, and most deadly, cancers that affected due to a huge burden of viral hepatitis transmission and disease.

Advances in cancer research have made a vaccine designed to prevent cancer available. In 2006, the US FDA approved a human papilloma virus vaccine, called Gardasil. The vaccine protects against four HPV types, which together cause 70% of cervical cancers and 90% of genital warts. In March 2007, the US CDC Advisory Committee on Immunization Practices (ACIP) officially recommended that females aged 11-12 receive the vaccine, and indicated that females as young as age 9 and as old as age 26 are also candidates for immunization.

In addition to viruses, researchers have noted a connection between bacteria and certain cancers. The most prominent example is the link between chronic infection of the wall of the stomach with Helicobacter pylori and gastric cancer. Although only a minority of those infected with Helicobacter go on to develop cancer, since this pathogen is quite common it is probably responsible for the majority of these cancers.

Hormonal imbalances

Some hormones can act in a similar manner to non-mutagenic carcinogens in that they may stimulate excessive cell growth. A well-established example is the role of hyperestrogenic states in promoting endometrial cancer.

Immune system dysfunction

HIV is associated with a number of malignancies, including Kaposi’s sarcoma, non-Hodgkin’s lymphoma, and HPV-associated malignancies such as anal cancer and cervical cancer. AIDS-defining illnesses have long included these diagnoses. The increased incidence of malignancies in HIV patients points to the breakdown of immune surveillance as a possible etiology of cancer. Certain other immune deficiency states (e.g. common variable immunodeficiency and IgA deficiency) are also associated with increased risk of malignancy.

Heredity

Most forms of cancer are “sporadic”, and have no basis in heredity. There are, however, a number of recognized syndromes of cancer with a hereditary component, often a defective tumor suppressor allele. Famous examples are:

• certain inherited mutations in the genes BRCA1 and BRCA2 are associated with an elevated risk of breast cancer and ovarian cancer
• tumours of various endocrine organs in multiple endocrine neoplasia (MEN types 1, 2a, 2b)
• Li-Fraumeni syndrome (various tumors such as osteosarcoma, breast cancer, soft tissue sarcoma, brain tumors) due to mutations of p53
• Turcot syndrome (brain tumors and colonic polyposis)
• Familial adenomatous polyposis an inherited mutation of the APC gene that leads to early onset of colon carcinoma.
• Hereditary nonpolyposis colorectal cancer (HNPCC, also known as Lynch syndrome) can include familial cases of colon cancer, uterine cancer, gastric cancer, and ovarian cancer, without a preponderance of colon polyps.
• Retinoblastoma, when occurring in young children, is due to a hereditary mutation in the retinoblastoma gene.
• Down syndrome patients, who have an extra chromosome 21, are known to develop malignancies such as leukemia and testicular cancer, though the reasons for this difference are not well understood.

Other causes

A few types of cancer in non-humans have been found to be caused by the tumor cells themselves. This phenomenon is seen in dogs with Sticker’s sarcoma, also known as canine transmissible venereal tumor, as well as Devil facial tumour disease in Tasmanian devils. The closest known analogue to this in humans is individuals who have developed cancer from transplacental transmission or from organ transplants.

In the United States every year, approximately 3,500 pregnant women have a malignancy, and transplacental transmission of acute leukaemia, lymphoma, melanoma and carcinoma from mother to fetus has been observed.

The development of donor-derived tumors from organ transplants is exceedingly rare. The main cause of organ transplant associated tumors seems to be malignant melanoma that was undetected at the time of organ harvest.

Cervix cancer is a number one disease that kill women in Indonesia

Each year, there are 15 thousands new case and 8 thousands women are die cause of this disease. Many humans die are cause of minimum information about cervix cancer, especially women. In Fact, all women have risk to hit cancer which can attack their main organ.

Women cancer
According research result, cancer cause often attack women (after breast cancer) such as; Ovarium cancer, cervix cancer and uterus cancer. Women reproduction content are 2 ovarium, 2 tuba fallopian, uterus, cervix, and vagina.

Ovarium cancer is part of gynaecology that often happen, cause of women have prosperity increasing therefore they didn’t want to born a child. Recorded 190 thousands case in the world with death number till 115 thousands. cervix cancer is the first level in obstetrics and gynaecology cancer case, but when founded preventive and early ‘skrining’ detection, cervix cancer patient have decrease. Recorded 500 thousands case in the world with death number till 250 thousands.

Uterus cancer is cancer that often happen in endometrial, a place where fetus growing, often happen to women ages 60-70 years old.